產(chǎn)品編號(hào) | bs-18659R-Gold |
英文名稱 | Rabbit Anti-MAP1D/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的蛋氨酸氨肽酶1D抗體 |
別 名 | AMP1D_HUMAN; CDS of metAP 3 within PCR fragment; M ethionine aminopeptidase 1D, mitochondrial precursor; MAP 1D; MAP1D; MetAP 1D; Metap1l; Methionine aminopeptidase 1D; Methionine aminopeptidase 1D, mitochondrial; Methionyl aminopeptidase type 1D (mitochondrial); Methionyl aminopeptidase type 1D, mitochondrial; mitochondrial; Peptidase M 1D. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Dog, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 35kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MAP1D |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]).[supplied by OMIM, Mar 2008] Function: Removes the amino-terminal methionine from nascent proteins (By similarity). May play a role in colon tumorigenesis. Subcellular Location: Mitochondrion. Tissue Specificity: Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). Similarity: Belongs to the peptidase M24A family. Database links: Entrez Gene: 254042 Human Entrez Gene: 66559 Mouse Omim: 610267 Human SwissProt: Q6UB28 Human SwissProt: Q9CPW9 Mouse Unigene: 298250 Human Unigene: 152796 Mouse Unigene: 24026 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |