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Rabbit Anti-ANKRD1/Gold Conjugated antibody (bs-8074R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-8074R-Gold
英文名稱 Rabbit Anti-ANKRD1/Gold Conjugated antibody
中文名稱 膠體金標記的心肌錨蛋白重復(fù)結(jié)構(gòu)域1抗體
別    名 ALRP; ANKR1_HUMAN; ANKRD 1; ANKRD1; Ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain containing protein 1; Ankyrin repeat domain-containing protein 1; C 193; C193; Cardiac ankyrin repeat protein; CARP; CVARP; Cytokine inducible nuclear protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; HA1A2; Liver ankyrin repeat domain 1; MCARP.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  心血管  細胞生物  免疫學  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANKRD1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.

Function:
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.

Subunit:
Interacts with YBX1 (By similarity). Interacts with TTN/titin.

Subcellular Location:
Nucleus.

Tissue Specificity:
Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.

DISEASE:
Defects in ANKRD1 may be a cause of total anomalous pulmonary venous return (TAPVR) . TAPVR is a rare congenital heart disease (CHD) in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a prevalence of approximately 1 out of 15'000 live births.

Similarity:
Contains 5 ANK repeats.

Database links:

Entrez Gene: 27063 Human

Entrez Gene: 107765 Mouse

Entrez Gene: 27064 Rat

Omim: 609599 Human

SwissProt: Q15327 Human

SwissProt: Q9CR42 Mouse

SwissProt: Q8R560 Rat

Unigene: 448589 Human

Unigene: 10279 Mouse

Unigene: 3789 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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