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Anti-human CLDN18.2 (Zolbetuximab Biosimilar) (BIO0138SM)  
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產(chǎn)品編號 BIO0138SM
英文名稱 Anti-human CLDN18.2 (Zolbetuximab Biosimilar)
中文名稱
抗體來源
克隆類型 Monoclonal
克 隆 號
交叉反應(yīng) Human
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 150 kDa
檢測分子量
性    狀 Lyophilized
亞    型 Human IgG1
純化方法 Protein A
保存條件 For long term storage, the produce should be stored at -20°C or lower.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹
產(chǎn)品圖片
Zolbetuximab inhibited the tumor growth of CLDN18.2-MC38 (Mouse colorectal cancer cells) on C57BL/6N mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 42.3% at 10 mpk at D25.
Immobilized human CLDN18.2 VLP at 2 ug/mL can bind Anti-CLDN18.2 Reference Antibody (zolbetuximab), EC50=0.07951 ug/mL.
The purity of Anti-CLDN18.2 Reference Antibody (zolbetuximab) is 96.05%, determined by SEC-HPLC.
Anti-CLDN18.2 Reference Antibody (zolbetuximab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
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