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SHISA5 Rabbit pAb (bs-21185R)  
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產(chǎn)品編號(hào) bs-21185R
英文名稱 SHISA5 Rabbit pAb
中文名稱 SHISA5蛋白抗體
別    名 pProtein shisa 5; Putative NF kappa B activating protein 120; Putative NFkB activating protein 120; Scotin; Shisa homolog 5(Xenopus laevis); SHSA5_HUMAN.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞凋亡  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 26 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SHISA5: 41-140/240 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Function:
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.

Subunit:
Interacts with PDCD6; PDCD6 can stabilze SHISA5.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane.

DISEASE:
Induced in a p53/TP53-dependent manner in response to cellular stress

SWISS:
Q8N114

Gene ID:
51246

Database links:

Entrez Gene: 51246 Human

Omim: 607290 Human

SwissProt: Q8N114 Human

Unigene: 414579 Human



產(chǎn)品圖片
Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti-SHISA5 (bs-21185R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kD Observed band size: 26 kD
Sample: A549(Human) Cell Lysate at 30 ug Primary: Anti-SHISA5 (bs-21185R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kD Observed band size: 26 kD
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