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PAPD4 Rabbit pAb (bs-21076R)  
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產(chǎn)品編號(hào) bs-21076R
英文名稱 PAPD4 Rabbit pAb
中文名稱 PAP相關(guān)結(jié)構(gòu)域蛋白4抗體
別    名 8030446C20Rik; AI649009; FLJ38499; GLD 2; Gld2; GLD2_HUMAN; hGLD 2; hGLD-2; MGC93684; PAD 4; PAP associated domain containing 4; PAP-associated domain-containing protein 4; papd4; Poly(A) RNA polymerase GLD2; Terminal uridylyltransferase 2; TUTase 2.  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAPD4: 31-130/484 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 PAPD4 (Poly(A) RNA Polymerase D4, Non-Canonical) is a Protein Coding gene. GO annotations related to this gene include polynucleotide adenylyltransferase activity. An important paralog of this gene is ZCCHC6.

Function:
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla.

Similarity:
Belongs to the DNA polymerase type-B-like family. GLD2 subfamily.
Contains 1 PAP-associated domain.

SWISS:
Q6PIY7

Gene ID:
167153

Database links:

Entrez Gene: 167153 Human

Entrez Gene: 100715 Mouse

GenBank: BC026061 Human

SwissProt: Q6PIY7 Human

SwissProt: Q91YI6 Mouse

Unigene: 418198 Human

Unigene: 242865 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PAPD4) Polyclonal Antibody, Unconjugated (bs-21076R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PAPD4) Polyclonal Antibody, Unconjugated (bs-21076R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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