產(chǎn)品編號(hào) | bs-21076R |
英文名稱 | PAPD4 Rabbit pAb |
中文名稱 | PAP相關(guān)結(jié)構(gòu)域蛋白4抗體 |
別 名 | 8030446C20Rik; AI649009; FLJ38499; GLD 2; Gld2; GLD2_HUMAN; hGLD 2; hGLD-2; MGC93684; PAD 4; PAP associated domain containing 4; PAP-associated domain-containing protein 4; papd4; Poly(A) RNA polymerase GLD2; Terminal uridylyltransferase 2; TUTase 2. |
研究領(lǐng)域 | 細(xì)胞生物 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 56 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PAPD4: 31-130/484 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
PAPD4 (Poly(A) RNA Polymerase D4, Non-Canonical) is a Protein Coding gene. GO annotations related to this gene include polynucleotide adenylyltransferase activity. An important paralog of this gene is ZCCHC6. Function: Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla. Similarity: Belongs to the DNA polymerase type-B-like family. GLD2 subfamily. Contains 1 PAP-associated domain. SWISS: Q6PIY7 Gene ID: 167153 Database links: Entrez Gene: 167153 Human Entrez Gene: 100715 Mouse GenBank: BC026061 Human SwissProt: Q6PIY7 Human SwissProt: Q91YI6 Mouse Unigene: 418198 Human Unigene: 242865 Mouse |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PAPD4) Polyclonal Antibody, Unconjugated (bs-21076R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PAPD4) Polyclonal Antibody, Unconjugated (bs-21076R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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