產(chǎn)品編號 | bs-19621R |
英文名稱 | PADI3 / PAD3 Rabbit pAb |
中文名稱 | 蛋白質(zhì)精氨酸亞型3抗體 |
別 名 | HL-60 PAD; HPAD10; PAD; PAD4; PADI; PADI H protein; Padi4; PADI3_HUMAN; PADI5; PDI; PDI1; PDI2; PDI3; PDI4; PDI5; peptidyl arginine deiminase type I; peptidyl arginine deiminase type II; peptidyl arginine deiminase type III; peptidyl arginine deiminase type IV; peptidyl arginine deiminase type VI; Peptidyl arginine deiminase, type V; Peptidylarginine deiminase; Peptidylarginine deiminase IV; Peptidylarginine deiminase type VI; Protein-arginine deiminase type I; Protein-arginine deiminase type II; Protein-arginine deiminase type III; Protein-arginine deiminase type IV; Protein-arginine deiminase type-4. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號 | |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 75 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PADI3 / PAD3: 1-100/664 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] Function: Catalyzes the deimination of arginine residues of proteins. Subcellular Location: Cytoplasm. Tissue Specificity: Hair follicles, and epidermis at very low levels. Similarity: Belongs to the protein arginine deiminase family. SWISS: Q9ULW8 Gene ID: 51702 Database links: Entrez Gene: 51702 Human Entrez Gene: 18601 Mouse Omim: 606755 Human SwissProt: Q9ULW8 Human SwissProt: Q9Z184 Mouse Unigene: 149195 Human Unigene: 20851 Mouse Unigene: 32094 Rat |
產(chǎn)品圖片 |
Sample:
Pancreas (Mouse) Lysate at 40 ug
Primary: Anti-PADI3 / PAD3 (bs-19621R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 75 kD
Observed band size: 75 kD
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