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Mouse P Glycoprotein Ready-To-Use IHC Kit (IHC0264M)  
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產(chǎn)品編號 IHC0264M
英文名稱 Mouse P Glycoprotein Ready-To-Use IHC Kit
中文名稱 小鼠P-糖蛋白即用型免疫組化試劑盒
別    名 ABC20; ABCB1; Abcb1a; Abcb1b; Abcb4; CD243; CLCS; Evi32; GP170; mdr; mdr-3; MDR1; Mdr1a; Mdr1b; Mdr3; P-GP; Pgp; PGP1; PGP2; Pgy-1; Pgy-3; PGY1; Pgy1-1; PGY2; Pgy3; ATP binding cassette; sub family B (MDR/TAP); member 1; ATP-binding cassette sub-family B member 1; Colchicin sensitivity; Doxorubicin resistance; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1  
克 隆 號
適用樣品基質(zhì) FFPE tissue
保存條件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

SWISS:
P08183

Gene ID:
5243

產(chǎn)品圖片
Immunohistochemical analysis of paraffin embedded mouse kidney tissue slide using IHC0264M (Mouse P Glycoprotein IHC Kit).
Immunohistochemical analysis of paraffin embedded mouse brain tissue slide using IHC0264M (Mouse P Glycoprotein IHC Kit).
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